KINETICS OF SERUM AMINOSALICYLIC ACID LEVELS

Para-Aminosalicylic Acid: Pas

Failure of P-(di-n-propylsulfamyl)-benzoic acid (benemid) to influence p-aminosalicylic acid blood levels.

aminosalicylic acid to 5-aminosalicylic acid in topical treatment of ulcerative colitis. Digestion

Ester Prodrug of 5-Aminosalicylic Acid for Colon Specific Drug Delivery: Synthesis, Kinetics, Hydrolysis and Stabilities

Acrylic type polymeric systems having degradable ester bonds linked to the 5-aminosalicylic acid (5-ASA), were synthesized and evaluated for colon targeted drug delivery. The obtained prodrug was characterized by FTIR,HNMR,Melting point and Rf value.In vitro drug release study was conducted at pH 1.2,7.4 and in rat fecal matter. Drug release in rat fecal matter at pH 7.4 was found to be most sa...

Reduction of serum cholesterol concentrations by neomycin, para-aminosalicylic acid, and other antibacterial drugs in man.

Fifty-six patients were studied in 112 experimental periods of 2 to 37 weeks. Twenty-seven patients were male and 29 were female, with an age range of 21 to 76 years. Forty patients were hospitalized and 16 were outpatients. Hospitalized patients were maintained on regular hospital diets in which 40 to 45 per cent of the calories were derived from fat. The food intake of the 16 outpatients was ...